2. Signaling Pathways
  3. GPCR/G Protein
  4. GnRH Receptor
  5. GnRH Receptor Inhibitor

GnRH Receptor Inhibitor

GnRH Receptor Inhibitors (4):

Cat. No. Product Name Effect Purity
  • HY-B1012
    Quinestrol
    		Inhibitor 99.72%
    Quinestrol (W-3566) is an orally effective synthetic estrogen compound that acts on CYP3A4, CYP1A2, and GnRH. Quinestrol interferes with GnRH release and disrupts the hypothalamic-pituitary-ovarian axis. Quinestrol downregulates the gene expression of follicle-stimulating hormone β and luteinizing hormone β, induces oxidative stress, damages reproductive organs, reduces sperm density and motility, increases sperm malformation rate, and alters the levels of sex hormones such as testosterone, luteinizing hormone, estradiol, and progesterone. Quinestrol can be used in studies related to reproductive function regulation.
  • HY-139303
    LUF5771
    		Inhibitor 99.49%
    LUF5771 is a potent allosteric recombinant luteinizing hormone (recLH) and Org 43553 inhibitor. LUF5771 is able to partially activate the LH receptor with low efficacy.
  • HY-164032
    Dimethandrolone undecanoate
    		Inhibitor
    Dimethandrolone undecanoate (7α,11β-Dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate) exhibits withrogens and progesterone activity. Dimethandrolone undecanoate inhibits production of gonadotropins, suppresses testosterone production, and thus inhibits sperm production. Dimethandrolone undecanoate is potent for development of male hormone contraceptives.
  • HY-P0013A
    Antide acetate
    		Inhibitor
    Antide (D-21074) acetate is a potent LHRH antagonist. Antide also can be used for the research of prostatic cancer.